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Pei-Ching Chang,1 Chia-Lin Hsu,2 Shao-Yu Tai,2 Aileen I Tsai,2 I-Kuan Wang,3 Cheng-Hao Weng,4 Wen-Hung Huang,4 Ching-Wei Hsu,4 Tzung-Hai Yen4–6
1Division of Pediatric Dentistry, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 2Division of Pediatric Dentistry, Chang Gung Memorial Hospital, Linkou, Taiwan; 3Division of Nephrology, China Medical College Hospital and Faculty of Medication, China Medical College, Taichung, Taiwan; 4Division of Nephrology and Scientific Poison Heart, Chang Gung Memorial Hospital and Faculty of Medication, Chang Gung College, Linkou, Taiwan; 5Kidney Analysis Heart, Chang Gung Memorial Hospital, Linkou, Taiwan; 6Heart for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan
Correspondence: Tzung-Hai Yen
Division of Nephrology and Scientific Poison Heart, Chang Gung Memorial Hospital and Faculty of Medication, Chang Gung College, 199 Tung Hwa North Street, Taipei 105, Taiwan
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Function: A consensus in regards to the pathogenesis of torus palatinus (TP) in sufferers receiving dialysis nonetheless eludes the scientific group. This potential observational research investigated the epidemiology of TP in peritoneal dialysis and hemodialysis sufferers and analyzed the influences of a number of pathogenic elements reminiscent of mineral and bone problems, genetic, environmental or dietary triggers, development of age, heredity, climatologic or biomechanical causes, and hyperparathyroidism on the formation of TP.
Strategies: Between 2013 and 2016, a complete of 575 continual dialysis sufferers (441 on hemodialysis and 134 on peritoneal dialysis) had been recruited from Chang Gung Memorial Hospital, Taiwan. Sufferers had been stratified into two teams based mostly on the presence (n = 179) or absence (n = 396) of TP. Demographic, oral examination, laboratory, and dialysis information had been collected for evaluation. Scholar’s t-test was used to research the quantitative variables and Chi-square or Fisher’s actual take a look at for categorical variables. Univariate binary logistic regression evaluation was carried out to find out the predictors for TP and multivariate binary logistic regression evaluation to establish important related elements.
Outcomes: The prevalence of TP in dialysis sufferers on this research was 31.1% (28.3% for hemodialysis and 40.3% for peritoneal dialysis). Sufferers with TP had been youthful (54.6 ± 13.Four versus 58.9 ± 14.7 years, P = 0.001) and largely feminine (60.Three versus 41.2%, P < 0.001). Most TP instances (55.3%) had been small in dimension (< 2 cm), with the flat form (56.4%) being the most typical adopted by the spindle (17.9%), nodular (17.3%), and lobular (8.4%) shapes. An extended period of dialysis was related to TP ≥ 2 cm than with TP < 2 cm (94.4 ± 85.9 versus 72.8 ± 59.1 months, P = 0.048). Multivariate logistic regression revealed that feminine gender (odds ratio 2.108, 95% confidence interval 1.455– 3.055, P < 0.001) and youthful age (odds ratio 0.982; 95% confidence interval 0.969– 0.994, P = 0.005) had been important predictors for TP.
Conclusion: The prevalence of TP in continual dialysis sufferers is 31.1%, larger in sufferers receiving peritoneal dialysis (40.3%) than hemodialysis (28.3%). Feminine gender and youthful age are important predictors related to TP.
Key phrases: end-stage renal illness, hemodialysis, peritoneal dialysis, torus palatinus
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