• Latest
  • Trending
  • All
  • Transplant
  • Dialysis
  • Donation
What We Don’t Know About the Coronavirus

What We Don’t Know About the Coronavirus

‘Miracle baby’ celebrates anniversary of life-saving liver transplant

‘Miracle baby’ celebrates anniversary of life-saving liver transplant

Too many donor kidneys are discarded in U.S. before transplantation

Too many donor kidneys are discarded in U.S. before transplantation

COVID-19 impact on the Medical Supplies Market by Type & End-user

Global Dialysis Devices and Equipment Market Opportunities and Strategies to 2030 with Fresenius Medical Care, Baxter International, Nipro, B Braun Melsungen & Medtronic Dominating

Joey Gase back with Rick Ware Racing for 2021

Joey Gase back with Rick Ware Racing for 2021

Students push to change organ donor registry in hopes of saving more lives

Change organ donor registry to save more lives, students say

New York Baby Survives COVID, Has Liver Transplant—All Before Turning One

New York Baby Survives COVID, Has Liver Transplant—All Before Turning One

Suspending kidney transplants will see organs wasted, says man on waiting list

Suspending kidney transplants will see organs wasted, says man on waiting list

Impact of COVID-19 on Renal Dialysis Market by 2027 |Onyx Solar Group, Shenzhen Topray Solar, Borosil Glass Works Limited, Trina Solar, Ja Solar Holdings Co

Impact of COVID-19 on Renal Dialysis Market by 2027 |Onyx Solar Group, Shenzhen Topray Solar, Borosil Glass Works Limited, Trina Solar, Ja Solar Holdings Co

Dialysis Market Latest Research Forecast 2020-2029 | Top Players: Fresenius Medical Care AG & Co KGaA, Baxter International Inc, DaVita Inc

Regenerative Therapies Market Size to Expand at Highest Revenue US$ 45,940.7 Million by 2027, Owing to Rapid Growth of Stem Cell Businesses

Congress extends Medicare coverage of immunosuppressive drugs for kidney transplant

UH researcher working to identify potential new therapeutic targets for kidney disease

Akron teen among first in region treated with special antibody therapy for COVID-19

Akron teen among first in region treated with special antibody therapy for COVID-19

IT Solution for Dialysis Market by types, applications, countries, companies and forecasts to 2027 covered in a latest research – The Courier

IT Solution for Dialysis Market by types, applications, countries, companies and forecasts to 2027 covered in a latest research – The Courier

  • Privacy Policy
  • Terms and Conditions
  • About Us
  • Contact Us
Friday, January 15, 2021
Transplant News
No Result
View All Result
  • Home
  • Transplant
    • All
    • Kidney Transplant
    ‘Miracle baby’ celebrates anniversary of life-saving liver transplant

    ‘Miracle baby’ celebrates anniversary of life-saving liver transplant

    Too many donor kidneys are discarded in U.S. before transplantation

    Too many donor kidneys are discarded in U.S. before transplantation

    New York Baby Survives COVID, Has Liver Transplant—All Before Turning One

    New York Baby Survives COVID, Has Liver Transplant—All Before Turning One

    Suspending kidney transplants will see organs wasted, says man on waiting list

    Suspending kidney transplants will see organs wasted, says man on waiting list

    Congress extends Medicare coverage of immunosuppressive drugs for kidney transplant

    UH researcher working to identify potential new therapeutic targets for kidney disease

    Akron teen among first in region treated with special antibody therapy for COVID-19

    Akron teen among first in region treated with special antibody therapy for COVID-19

    Retired Springfield teacher in need of liver transplant | News

    Retired Springfield teacher in need of liver transplant | News

    Woman’s kidney transplant surgery delayed due to COVID-19 surge

    Woman’s kidney transplant surgery delayed due to COVID-19 surge

    Heart transplant on hold because of excess of COVID patients

    Heart transplant on hold because of excess of COVID patients

    Race-Based Equation May Delay Kidney Transplant Eligibility for Black Patients

    Race-Based Equation May Delay Kidney Transplant Eligibility for Black Patients

  • Donation
    • All
    • Kidney Donation
    • Liver Donation
    • Organ Donation
    Joey Gase back with Rick Ware Racing for 2021

    Joey Gase back with Rick Ware Racing for 2021

    Dialysis Market Latest Research Forecast 2020-2029 | Top Players: Fresenius Medical Care AG & Co KGaA, Baxter International Inc, DaVita Inc

    Regenerative Therapies Market Size to Expand at Highest Revenue US$ 45,940.7 Million by 2027, Owing to Rapid Growth of Stem Cell Businesses

    Highland politician Edward Mountain in plea for transplant patients to be prioritised for Covid-19 vaccine

    Highland politician Edward Mountain in plea for transplant patients to be prioritised for Covid-19 vaccine

    MTF Biologics Awards Over $1 Million in 2020 Extramural Research Grants and Announces Timeline for 2021 Applications

    MTF Biologics Awards Over $1 Million in 2020 Extramural Research Grants and Announces Timeline for 2021 Applications

    2 men arrested after 2 Greenville teen girls shot; murder charge looming

    2 men arrested after 2 Greenville teen girls shot; murder charge looming

    Newman Begins Chili Bowl Action Wednesday

    Newman Begins Chili Bowl Action Wednesday

    Kidney Stone Management Market Worth USD 2.21 Billion by 2027; Government-supported Reimbursement Policies to Help Gain Traction: Fortune Business Insights™

    Ultra-low Temperature Freezer Market to Reach USD 783.1 million by 2027; Rising Research in Life Science to Boost Growth: Fortune Business Insights™

    NJ Sharing Network Foundation names new board officers

    NJ Sharing Network Foundation names new board officers

    Highland politician in plea for transplant patients to be given vaccine priority

    Highland politician in plea for transplant patients to be given vaccine priority

    Should Medicare enrollees be ‘nudged’? New research reveals impact of default insurance plans

    Should Medicare enrollees be ‘nudged’? New research reveals impact of default insurance plans

  • Dialysis
    COVID-19 impact on the Medical Supplies Market by Type & End-user

    Global Dialysis Devices and Equipment Market Opportunities and Strategies to 2030 with Fresenius Medical Care, Baxter International, Nipro, B Braun Melsungen & Medtronic Dominating

    Impact of COVID-19 on Renal Dialysis Market by 2027 |Onyx Solar Group, Shenzhen Topray Solar, Borosil Glass Works Limited, Trina Solar, Ja Solar Holdings Co

    Impact of COVID-19 on Renal Dialysis Market by 2027 |Onyx Solar Group, Shenzhen Topray Solar, Borosil Glass Works Limited, Trina Solar, Ja Solar Holdings Co

    IT Solution for Dialysis Market by types, applications, countries, companies and forecasts to 2027 covered in a latest research – The Courier

    IT Solution for Dialysis Market by types, applications, countries, companies and forecasts to 2027 covered in a latest research – The Courier

    Dialysis Devices And Equipment Market Companies Are Investing In Technological Developments For Better Treatment Options

    Dialysis Devices And Equipment Market Companies Are Investing In Technological Developments For Better Treatment Options

    Ferric citrate shows benefits over ferrous sulfate for treating iron deficiency in CKD

    CDC, kidney community leaders push safety of COVID-19 vaccines for staff, patients

    Global Organ Transplant Market By Type, By Sex, By Product, By Organ, By Types of Transplant, By Region, Forecast & Opportunities, 2025

    Global Peritoneal Dialysis Industry

    Organ Transplant Industry Analysis 2015-2025 by Type, Sex, Product, Organ, Types of Transplant, Company and Region

    Insights on the Kidney Disease APAC Market to 2027

    Kidney Dialysis Centers Market | Company Challenges And Essential Success Factors |B. Braun Melsungen Ag, Baxter International Inc., Fresenius Medical Care Ag & Co. Kgaa, Davita Inc., Nipro Corporation, etc – Murphy’s Hockey Law

    Kidney Dialysis Centers Market | Company Challenges And Essential Success Factors |B. Braun Melsungen Ag, Baxter International Inc., Fresenius Medical Care Ag & Co. Kgaa, Davita Inc., Nipro Corporation, etc – Murphy’s Hockey Law

    COVID 19 Impact On Kidney Dialysis Equipment Market Latest Trends and Forecast Analysis Up to 2027

    COVID 19 Impact On Kidney Dialysis Equipment Market Latest Trends and Forecast Analysis Up to 2027

    ESRD and Medicare: Coverage, plans, and costs

    ESRD and Medicare: Coverage, plans, and costs

  • Donor
    • All
    • Kidney Donor
    • Organ Donor
    Students push to change organ donor registry in hopes of saving more lives

    Change organ donor registry to save more lives, students say

    Type mismatch made for TV

    Type mismatch made for TV

    Battery of charges against conman over kidney donors fraud- The New Indian Express

    Battery of charges against conman over kidney donors fraud- The New Indian Express

    Aubree Burton, 16, seeks kidney donor – Dorchester Banner

    Aubree Burton, 16, seeks kidney donor – Dorchester Banner

    Randolph County father of child battling cancer in search of kidney

    Father needs kidney donor as 2-year-old daughter battles brain cancer | WJHL

    “My life is not on the line here, but hers is;” Doctors forced to call off kidney donation surgery

    “My life is not on the line here, but hers is;” Doctors forced to call off kidney donation surgery

    House debates impeaching Pres. Trump; hidden ‘beer cave’ discovered in neighborhood – WKRG News 5

    Newsfeed Now: House debates impeaching Pres. Trump; hidden ‘beer cave’ discovered in neighborhood

    Milwaukee Radio Host’s Kidney Will Go To Someone In Need

    Milwaukee Radio Host’s Kidney Will Go To Someone In Need

    House debates impeaching Pres. Trump; hidden ‘beer cave’ discovered in neighborhood – WKRG News 5

    House debates impeaching Pres. Trump; hidden ‘beer cave’ discovered in neighborhood – WKRG News 5

    How beloved SF sports bar Underdogs survived a fire, a failed kidney and a pandemic

    How beloved SF sports bar Underdogs survived a fire, a failed kidney and a pandemic

  • Editor’s Pick
  • Videos
    Exercise and Lifestyle with Cardiomyopathy

    Exercise and Lifestyle with Cardiomyopathy

    BSC Renal Dialysis Technology Course career and scope in malayalam

    BSC Renal Dialysis Technology Course career and scope in malayalam

    On the other side, my experience as a stem cell donor

    On the other side, my experience as a stem cell donor

    Rehman Free Dialysis Center

    Rehman Free Dialysis Center

    Advances in Lung Transplant: Better Testing, Matching and Conditioning

    Advances in Lung Transplant: Better Testing, Matching and Conditioning

    Dialysis time

    Dialysis time

    Medical Treatment of Dilated Cardiomyopathy – Chet Patel, MD

    Medical Treatment of Dilated Cardiomyopathy – Chet Patel, MD

    Vlog088 "My Mini Dialysis Testimony"

    Vlog088 "My Mini Dialysis Testimony"

    MacLean Conference – Walter Glannon "Are We Underestimating the Risk in Living Kidney Donation?"

    MacLean Conference – Walter Glannon "Are We Underestimating the Risk in Living Kidney Donation?"

Transplant News
Home Dialysis

What We Don’t Know About the Coronavirus

in Dialysis
What We Don’t Know About the Coronavirus
492
SHARES
1.4k
VIEWS
Share on FacebookShare on Twitter

By writer to www.newyorker.com

It’s not solely the immune system that should keep a fragile stability. The bloodstream, too, exists in a perpetual tug-of-war between bleeding and clotting. An excessive amount of bleeding, and the smallest trauma may cause hemorrhage, even to the purpose of dying (the hazard confronted by folks with hemophilia); too far within the different course, and clots will type within the absence of trauma, probably obstructing blood vessels and inflicting deadly injury in the event that they journey to the guts, lungs, or mind.

By measuring a blood protein known as D-dimer, medical doctors can get a tough sense of how a lot extra clotting is occurring within the bloodstream. Many infections trigger an increase in clotting. However in some COVID-19 sufferers medical doctors are seeing jaw-dropping spikes. A number of sufferers seem to have widespread pathologic clotting. Considered one of our sufferers, a wholesome man in his fifties, arrived in our hospital’s I.C.U. with a D-dimer stage of a thousand—elevated however unremarkable. However when a health care provider tried to place an I.V. into one of many man’s femoral veins—the biggest veins within the legs—he found, by use of a bedside ultrasound, that it was crammed with clots. The second D-dimer take a look at, carried out simply hours after the primary, registered a stage of over ten thousand. The person died a number of hours later.

It’s attainable that cytokine storms are inflicting overactive clotting. However, regardless of the trigger seems to be, clinicians face a problem. Medical doctors usually give small doses of anticoagulant medicine to sufferers who’re admitted to the hospital, just because mendacity in mattress for an prolonged interval makes clotting extra doubtless. However extra excessive ranges of clotting demand extra aggressive anticoagulation—and medical doctors should determine when to manage it and to whom. These drugs carry their very own dangers. The affected person affected by femoral clotting was instantly placed on aggressive anticoagulation medicine. But his dying, and the speedy improve in his D-dimer, recommend that profitable anticoagulant interventions in different sufferers may have to return earlier.

Medical doctors usually take a look at critically unwell sufferers for cardiac-specific troponins—proteins within the bloodstream which can be usually discovered solely within the muscle tissue of the guts. The presence of such proteins in blood suggests coronary heart injury. Some extreme COVID-19 sufferers have elevated troponin ranges; their hearts look like broken. We’re not completely positive what’s inflicting the injury, although, and so we don’t know precisely find out how to deal with it.

One main explanation for coronary heart injury is oxygen hunger: it’s what occurs in a coronary heart assault, when the sudden obstruction of a coronary artery prevents oxygen from reaching coronary heart muscle. Hunger also can happen when failing lungs forestall oxygen from coming into the bloodstream, or when sepsis causes such a drop in blood strain that even correctly oxygenated blood can’t get to the guts quick sufficient. These issues are important, and, in broad phrases, medical doctors understand how to reply to them. There are, nonetheless, different potentialities. Maybe runaway clotting is choking off circulation vessel by vessel. Early experiences from China, in the meantime, instructed that the coronavirus could possibly be attacking the guts muscle straight, inflicting a syndrome generally known as myocarditis. Nobody is aware of for positive what the very best therapy for this type of myocarditis is likely to be. Some medical doctors have reported that steroids may help—and but steroids additionally act as an immunosuppressant. In important care, it’s usually onerous to carry one organ system into stability with out destabilizing one other.

An analogous story seems to be unfolding across the kidneys. Kidneys function filters for the blood, removing sure compounds and excreting them in urine, whereas regulating the exact composition of electrolytes that permit cells to perform. Full kidney failure is a dying sentence if it’s not shortly addressed. Sadly, many critically unwell COVID-19 sufferers are growing it. Simply as ventilators are substituting for failing lungs, so dialysis machines are taking up for failing kidneys. The toughest-hit areas of the nation are going through shortages of the sources wanted for dialysis: dialysis machines, the fluid used within the dialysis course of, and dialysis-trained nurses.

We don’t but understand how kidney damage performs out in COVID-19 sufferers. It’s doubtless that some folks will get well their kidney perform, whereas others may lose it completely. We additionally don’t know why individuals are going into kidney failure within the first place. As with the guts, it’s attainable that oxygen hunger is the issue. However some clinicians argue that the virus is attacking kidney cells straight—and there may be biopsy knowledge out of China that helps this thesis, too.

Nonetheless different organ techniques could also be concerned in COVID-19. The ACE-2 receptor protein, which is utilized by the coronavirus to enter human cells, resides not simply within the respiratory tract but additionally on cells within the abdomen, intestines, liver, kidneys, and mind. There are experiences of coronavirus sufferers with encephalitis—a probably deadly irritation of the mind—and indicators of an elevated incidence of stroke. In our hospital, we’ve got seen a number of COVID-19 sufferers affected by a extreme complication of diabetes known as diabetic ketoacidosis, regardless of having no historical past as diabetics.

Final month, we screened for COVID-19 by asking about fever and cough. Now we all know that the illness manifests in different methods, or typically proceeds with no signs in any respect. One affected person just lately arrived within the E.R. reporting three days of watery diarrhea and a day of nausea and vomiting; she stated that she felt weak however hadn’t skilled fevers, chills, sweats, or respiratory signs. Her oxygen saturation was within the low nineties; her chest X-ray was in line with COVID-19.

For us, and for a lot of medical doctors we all know, circumstances like these have turn into topics of consuming fascination. Throughout our few free moments, we share sufferers’ sky-high D-dimer ranges and swap theories concerning the sources of their discordant oxygen readings. Within the absence of information from randomized, potential trials, we seek for solutions on colleagues’ Twitter accounts, in interviews with Chinese language or Italian physicians, and in our sufferers’ charts. Our colleagues at Mount Sinai are actively embarking on dozens of analysis tasks, starting from ventilator-management methods to social determinants of COVID-19 mortality, however months will go earlier than these tasks give us goal perception into the illness. The determined want for readability is clear at each stage of the medical occupation. Earlier this month, The New England Journal of Drugs printed an observational, fifty-three-patient research of the antiviral drug remdesivir; many observers criticized the journal for publishing it, as a result of the trial had neither a management group nor randomization, and so no significant statistical conclusions could possibly be drawn from its outcomes. (Even its authors famous that precise measurement of the drug’s efficacy would require “ongoing randomized, placebo-controlled trials.”)

And but, because the historian of science Lorraine Daston writes in a recent essay, it’s pure to forged about for solutions on the daybreak of a pandemic. “At moments of utmost scientific uncertainty,” Daston writes, “remark, often handled because the poor relation of experiment and statistics in science, comes into its personal.” Confronting a brand new illness, medical doctors don’t have any alternative however to show to “suggestive single circumstances, placing anomalies, partial patterns.” Slowly, as our concepts about “what works and what doesn’t” assist inform us “what to check, what to rely,” the image clarifies. Till then, “we’re again within the seventeenth century, the age of ground-zero empiricism, and observing as if our lives trusted it.” One affected person at a time, we’ve got to work our means into the current.


Extra Medical Dispatches

— to www.newyorker.com

Share197Tweet123Share49
Previous Post

Obituary | Katherine Marie Gustafson-Burch | Kingman Daily Miner

Next Post

Strong turnout for bone marrow donor registry drive, more encouraged to sign up

Next Post
Strong turnout for bone marrow donor registry drive, more encouraged to sign up

Strong turnout for bone marrow donor registry drive, more encouraged to sign up

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Editor's Pick

Oahu woman gives priceless Thanksgiving gift
Editor's Pick

Oahu woman gives priceless Thanksgiving gift

An Oahu woman blessed another family with a priceless Thanksgiving gift. Doctor Maryellen Markley gave up a kidney to help...

Tom Brady Helps Lexington Mom Get New Kidney

Tom Brady Helps Lexington Mom Get New Kidney

Tom Brady Continues to do His Part in Saving Lives

Tom Brady Continues to do His Part in Saving Lives

Kidney donor surprises Long Island recipient with visit

Kidney donor surprises Long Island recipient with visit

Patriots’ Tom Brady on Mission to Help Mentor

San Francisco police officer donates kidney to save a stranger

San Francisco police officer donates kidney to save a stranger

People Turn Online To Find Organ Matches

People Turn Online To Find Organ Matches

Woman Who Underwent Historic Double Transplant Surgery To Get New Kidney

Woman Who Underwent Historic Double Transplant Surgery To Get New Kidney

Local family searching for a kidney donor

Local family searching for a kidney donor

New England Patriots Tom Brady Helps To Save The Life Of A Woman Needing A Lifesaving Kidney Transplant

New England Patriots Tom Brady Helps To Save The Life Of A Woman Needing A Lifesaving Kidney Transplant

More in need of organ transplants seek their own donors

More in need of organ transplants seek their own donors

Tom Brady honors mentor with donation to local organ transplant organization

Tom Brady honors mentor with donation to local organ transplant organization

Transplant News

Copyright © 2020 All rights reserved.

Navigate Site

  • Privacy Policy
  • Terms and Conditions
  • About Us
  • Contact Us

Follow Us

No Result
View All Result
  • Home
  • Transplant
    • Kidney Transplant
  • Donation
    • Kidney Donation
    • Liver Donation
    • Organ Donation
  • Dialysis
  • Donor
    • Kidney Donor
    • Organ Donor
  • Videos
  • Editor’s Pick

Copyright © 2020 All rights reserved.