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SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Might 20, 2021–
Medeor Therapeutics, Inc., a clinical-stage firm devoted to the event and commercialization of immunotherapies for transplantation, at the moment introduced that interim outcomes of its Section three examine scientific trial for MDR-101 cell remedy shall be introduced as a Fast Hearth Oral Presentation by lead Principal Investigator Dr. Dixon Kaufman of the College of Wisconsin on the American Transplant Congress (ATC) on June 7, 2021.
Medeor’s Section three tolerance examine is a randomized, multi-center examine evaluating the institution of useful immune tolerance in MDR-101 recipients of HLA-matched dwelling donor kidney transplants. That is the primary randomized, multi-center pivotal examine particularly designed to remove the usage of immunosuppressive anti-rejection medicine following transplant.
Presently, sufferers who obtain a kidney transplant are dependent upon a lifelong routine of immunosuppressive medicine – typically as much as 25 drugs a day – which can be related to a litany of uncomfortable side effects and toxicities, and restricted efficacy which in the end influence graft and affected person survival, such that 30% to 50% of all kidney transplants fail by 10 years. MDR-101 is a single-dose mobile remedy derived from a dwelling kidney donor’s blood. The remedy is designed to determine blended chimerism – the co-existence of each recipient-derived and donor-derived blood and immune cells – to permit HLA-matched dwelling donor kidney transplant recipients to discontinue immunosuppressive drug use whereas preserving long-term graft operate and survival.
Particulars of the oral presentation are as follows:
Presentation Title: MDR-101-MLK-MERCURY Kidney Transplant Tolerance Examine Replace
Session Title: Biomarkers, Immune Evaluation and Scientific Outcomes – III
Summary quantity: 223
Presentation Time: 5:00 pm – 5:05 pm ET
Medeor Therapeutics can also be internet hosting a digital symposium, “Reprogramming the Immune System to Protect Kidney Operate Put up Transplant” on Wednesday, June 17, 2021 at 7–eight pm ET to debate the most recent advances in organ transplant cell remedy to induce donor-specific immune tolerance and keep away from transplant kidney rejection. The symposium will embody a KOL roundtable that includes:
- Stephan Busque, M.D., Stanford College Medical Heart
- Dixon Kaufman, M.D., Ph.D., College of Wisconsin College of Medication and Public Well being
- Sanjeev Akkina, M.D., Loyola College Medical Heart
- Daniel Brennan, M.D., Medeor Therapeutics (moderator)
As well as, Medeor Therapeutics Chief Medical Officer Dr. Daniel Brennan will present an organization overview and replace on future plans.
To register for the symposium, please go to https://www.eventbrite.com/e/redefining-organ-transplants-virtual-symposium-june-17-2021-tickets-155809822373.
MDR-101 is a single dose mobile remedy manufactured from a dwelling kidney donor’s blood and peripheral stem cells. MDR-101 is meant to induce donor-specific immune tolerance as a way to avert transplant kidney rejection and thereby protect transplant kidney operate and survival with out the cumulative and severe uncomfortable side effects related to immunosuppressive medicine. Medeor’s Section three trial is supported partially by a grant from the California Institute for Regenerative Medicine. For extra data on Medeor’s Section three trial, please go to https://clinicaltrials.gov.
About Medeor Therapeutics, Inc.
Medeor Therapeutics is working to enhance the lives of transplant sufferers by eliminating or minimizing the necessity for a life-long routine of immunosuppressive medicines and their potential life-threatening uncomfortable side effects. Medeor’s Section three scientific examine is demonstrating the numerous alternatives of this one-time remedy. For extra data, go to www.medeortx.com.
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KEYWORD: CALIFORNIA UNITED STATES NORTH AMERICA
INDUSTRY KEYWORD: BIOTECHNOLOGY SURGERY HEALTH PHARMACEUTICAL CLINICAL TRIALS
SOURCE: Medeor Therapeutics, Inc.
Copyright Enterprise Wire 2021.
PUB: 05/20/2021 08:00 AM/DISC: 05/20/2021 08:02 AM
Copyright Enterprise Wire 2021.
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