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Transplantation. 2020 Nov 24. doi: 10.1097/TP.0000000000003557. On-line forward of print.
ABSTRACT
BACKGROUND: There’s restricted info regarding whether or not social determinants of well being have an effect on postliver transplant (LT) outcomes. This examine goals to grasp to what extent the well being of LT recipients’ counties of residence affect long-term LT outcomes.
METHODS: We used the United Community for Organ Sharing information to establish grownup LT recipients transplanted between January 2010 and June 2018. Affected person-level information had been matched to county-level County Well being Rating information utilizing transplant recipient zip code, and nationwide County Well being Rankings had been created. Blended-effects Cox proportional hazards fashions had been used to look at associations between County Well being Rankings and graft and affected person survival post-LT.
RESULTS: Well being Outcomes rank was considerably related to posttransplant graft and affected person survival, with worst tertile counties exhibiting a 13% elevated hazard of each graft failure and affected person mortality in comparison with greatest tertile counties.
CONCLUSIONS: Though county well being is related to LT outcomes, it additionally seems that LT recipient choice is efficient at mitigating main disparities primarily based on county of residence and helps yield equitable outcomes on this respect.
PMID:33239542 | DOI:10.1097/TP.0000000000003557
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