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J Clin Med. 2021 Sep 30;10(19):4533. doi: 10.3390/jcm10194533.
ABSTRACT
Herein, we carried out a meta-analysis of revealed medical outcomes of corona virus illness 2019 (COVID-19) in hospitalized kidney transplant recipients. A scientific database search was carried out between December 1, 2019 and April 20, 2020. We analyzed 48 research comprising 3137 kidney transplant recipients with COVID-19. Fever (77%), cough (65%), dyspnea (48%), and gastrointestinal signs (28%) have been predominant on hospital admission. The commonest comorbidities have been hypertension (83%), diabetes mellitus (34%), and cardiac illness (23%). The pooled prevalence of acute respiratory misery syndrome and acute kidney harm have been 58% and 48%, respectively. Invasive air flow and dialysis have been required in 24% and 22% sufferers, respectively. In-hospital mortality fee was as excessive as 21%, and elevated to over 50% for sufferers in intensive care unit (ICU) or requiring invasive air flow. Threat of mortality in sufferers with acute respiratory misery syndrome (ARDS), on mechanical air flow, and ICU admission was elevated: OR = 19.59, OR = 3.80, and OR = 13.39, respectively. Mortality danger within the aged was OR = 3.90; nonetheless, no such affiliation was noticed by way of time since transplantation and gender. Fever, cough, dyspnea, and gastrointestinal signs have been widespread on admission for COVID-19 in kidney transplant sufferers. Mortality was as excessive as 20% and elevated to over 50% in sufferers in ICU and required invasive air flow.
PMID:34640552 | DOI:10.3390/jcm10194533
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